“My opportunity finally came. In April 2018, I was one of a few hundred cystic fibrosis patients to dose in a pivotal phase III clinical trial to evaluate a new drug designed to correct CFTR, the dysfunctional protein responsible for …
Category: Protocols
Watch “Evidence Based Medicine Has Been Hijacked by Dr Aseem Malhotra | PHC Conference 2019” on YouTube
Insightful and fascinating glimpse into how medical science has been, and continues to be, distorted by special interests and ideological cabals to the detriment of patients.
Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base – ScienceDirect
“The benefits of carbohydrate restriction in diabetes are immediate and well documented. Concerns about the efficacy and safety are long term and conjectural rather than data driven. Dietary carbohydrate restriction reliably reduces high blood glucose, does not require weight loss …
Stem cell clinics co-opt clinicaltrials.gov to push unproven therapies – STAT
“When a judge ruled last week that the FDA could stop the work of U.S. Stem Cell, the firm’s trials remained on clinicaltrials.gov; the postings were no longer actively enlisting patients, but they didn’t mention that the company’s injections had …
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Aim your baloney detector at the BS in health care – STAT
BS, what Princeton philosopher Harry Frankfurt once calleda “lack of connection to a concern with truth — this indifference to how things really are,” has probably been around since the beginning of language. Health care has an acute BS problem, …
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Scientists rise up against statistical significance
Our call to retire statistical significance and to use confidence intervals as compatibility intervals is not a panacea. Although it will eliminate many bad practices, it could well introduce new ones. Thus, monitoring the literature for statistical abuses should be …
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The Pendulum Has Swung Too Far
“…an act, a habit, an institution, a law, gives birth not only to an effect, but to a series of effects. Of these effects, the first only is immediate; it manifests itself simultaneously with its cause—it is seen. The others …
