An analysis published in BMJ Open found that among primary prevention statin trials of 3.5-6 years duration, taking a daily statin only postponed death by a median of 3.2 days. Can we truly endorse a long-term therapy that might prolong life by a few days while ignoring the substantial long-term harms?
In his article, Dr Mandrola says that “numerous trials have shown that statins consistently reduce the risk of first cardiac events by about 20-25% in relative terms,” but a full accounting of statin trials finds that the benefits in primary prevention are inconsistent and modest, at best.
Source: A (different) perspective on statins in the primary prevention of heart disease
