Swedish researchers have preliminary findings suggesting that the Spike protein, from vaccine and/or natural infection has potential to enter the nucleus of our cells. Once inside the nucleus, it can possibly be mutagenic by promoting DNA damage or interfering with repair of damaged genes.
In short term, they postulate that this spike-nucleus interaction could inhibit our immune response. In long term, there was concern about enhanced expression of the BRC locus.
Obviously, we can’t “fix” the virus by getting rid of the spike protein. However, we have the ability to reformulate the SARS-CoV-2 vaccines by using the RBD fragment of the spike protein, which sits at the top and facilitates binding to ACE2 thus subsequent entry into our cells. The RBD is also where neutralizing antibodies attach.
Final point was that using whole-spike vaccines may lead to antibody-dependent enhancement of symptoms; thus refinements to vaccines [such as a conjugated polyvalent using RBD or other antigenic loci] may provide more efficacious & safer vaccines.
This research NEEDS to be checked and repeated to see if replicable.
https://youtu.be/4Unt03UBhbU